This issue of a+u examines the application of computational design and digital fabrication across a spectrum of scales - from a free-form high-rise exoskeleton, to bio-mimetic wearables for the body, to the printed structure of a nonstandard brick - taking its conceptual cues from Charles and Ray Eames' 1977 film, Powers of Ten. Selected here are 14 projects by individuals and entities working in cross-disciplinary ways, that suggest what“thinking digitally”can do with the means of our present time.